CCDC127

Across TCGA cell cohorts, CCDC127 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,595 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCDC127-associated GO terms across cancer lineages are Protein polyubiquitination, Regulation of transcription initiation by RNA polymerase II, and Process utilizing autophagic mechanism. Each is linked with CCDC127 in more than 15 cancer types. Because this analysis shows association rather than direction, both CCDC127-to-partner and partner-to-CCDC127 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein polyubiquitination grouped by CCDC127-low versus CCDC127-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC127→partner) and Y-score (partner→CCDC127) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Protein polyubiquitination →	+0.063	+0.831	<.001	.001	3	16
UPPER_AERODIGESTIVE_TRACT	Regulation of transcription initiation by RNA polymerase II →	+0.085	+0.974	<.001	<.001	3	14
OESOPHAGUS	Process utilizing autophagic mechanism →	+0.081	+0.987	.001	<.001	3	14
OESOPHAGUS	Autophagy →	+0.081	+0.987	.001	<.001	3	14
STOMACH	Regulation of myoblast fusion →	+0.122	+0.713	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Regulation of DNA-templated transcription initiation →	+0.078	+0.886	<.001	.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,595 associations by consensus.

Protein polyubiquitination by CCDC127 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →