CCDC126

Across TCGA patient cohorts, CCDC126 mutation is significantly associated with the RNA expression of many other genes, with 764 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC126-associated genes across cancer lineages are AQP7P5, RN7SL132P, and SLC2AXP1. Each is linked with CCDC126 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC126-to-partner and partner-to-CCDC126 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AQP7P5 grouped by CCDC126-low versus CCDC126-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC126→partner) and Y-score (partner→CCDC126) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	AQP7P5 →	+0.127	+5.302	<.001	.001	3	2
UCEC	RN7SL132P →	+0.091	+2.674	.006	.006	3	2
SKCM	SLC2AXP1 →	+0.070	+5.744	<.001	<.001	3	1
UCEC	WASL-DT →	+0.617	+2.743	<.001	.003	3	1
UCEC	CHASERR →	+0.650	+3.625	.003	.001	3	1
UCEC	H4C12 →	+0.610	+2.721	.003	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 764 associations by consensus.

AQP7P5 by CCDC126 expression — SKCM

Explore this box plot interactively →