Across TCGA patient cohorts, CCDC125 protein abundance is significantly associated with the RNA expression of many other genes, with 1,983 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CCDC125-associated genes across cancer lineages are LY6E, MICALL1, and POLR2F. Each is linked with CCDC125 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC125-to-partner and partner-to-CCDC125 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC125→partner) and Y-score (partner→CCDC125) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LY6E →	-1.167	-0.514	<.001	.003	3	2
BRCA	MICALL1 →	-0.922	-0.730	<.001	<.001	3	1
BRCA	POLR2F →	-0.774	-0.620	<.001	.001	3	1
BRCA	XBP1 →	+1.384	+0.469	<.001	<.001	3	1
BRCA	JOSD1 →	-0.377	-0.516	.002	.003	3	1
BRCA	MCM5 →	-0.694	-0.502	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,983 associations by consensus.

Exploration

CCDC125 survival (RNA) · tumor vs normal (RNA) · all CCDC125 data types