CCDC124

Across TCGA cell cohorts, CCDC124 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCDC124-associated genes across cancer lineages are PHOX2B, APOL5, and KLRD1. Each is linked with CCDC124 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC124-to-partner and partner-to-CCDC124 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PHOX2B grouped by CCDC124-low versus CCDC124-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC124→partner) and Y-score (partner→CCDC124) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	PHOX2B →	+0.024	+4.365	<.001	.002	3	1
BLOOD_Leukemia	APOL5 →	+0.012	+4.060	.002	.003	3	1
BLOOD_Leukemia	KLRD1 →	+0.163	+3.769	<.001	.008	3	1
BLOOD_Leukemia	SMIM23 →	+0.018	+4.984	<.001	.002	3	1
BLOOD_Leukemia	MORN5 →	+0.269	+3.855	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

PHOX2B by CCDC124 expression — BLOOD_Leukemia

Explore this box plot interactively →