CCDC124

Across TCGA pan-cancer cohorts, CCDC124 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of CCDC124’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where CCDC124 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CCDC124 is over-expressed in tumor.

KIRC, COAD, and KIRP are the cancer types where CCDC124 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CCDC124 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	IV	+0.578	<.001	12	view →
COAD	Female	All	+0.987	<.001	11	view →
KIRP	All	II,III,IV	+0.624	<.001	10	view →
LIHC	Female	II,III,IV	+1.347	<.001	9	view →
HNSC	Male	III,IV	+0.658	<.001	8	view →
LUSC	Male	II,III,IV	+0.711	<.001	6	view →
STAD	All	II,III,IV	+0.603	.001	6	view →
UCEC	All	All	+0.560	<.001	6	view →
BLCA	All	All	+0.417	.013	4	view →
CHOL	Female	All	+1.886	<.001	3	view →
BRCA	All	All	+0.246	.035	2	view →
ESCA	All	All	+0.861	.007	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

CCDC124–KIRC

Open the KIRC breakdown →