CCDC122

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CCDC122 mutation is significantly associated with the RNA expression of many other genes, with 2,141 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC122-associated genes across cancer lineages are RN7SKP149, RNU1-57P, and RNA5SP182. Each is linked with CCDC122 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC122-to-partner and partner-to-CCDC122 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SKP149 grouped by CCDC122-low versus CCDC122-high in STAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC122→partner) and Y-score (partner→CCDC122) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADRN7SKP149 →+0.200+3.505<.001.00832
STADRNU1-57P →+0.404+4.026<.001.00232
UCECRNA5SP182 →+0.285+3.877.001.00132
SKCMMIR6803 →+0.981+6.328<.001.00132
UCECHSPE1-MOB4 →+0.219+3.078<.001<.00131
UCECRPS10-NUDT3 →+0.389+3.183<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,141 associations by consensus.

RN7SKP149 by CCDC122 expression — STAD

Box plot of RN7SKP149 in CCDC122-low vs CCDC122-high samples in STAD.

Explore this box plot interactively →

Exploration