CCDC122

Across TCGA cell cohorts, CCDC122 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,526 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible CCDC122-associated GO terms across cancer lineages are Establishment of protein localization to plasma membrane, Integrin-mediated signaling pathway, and Vesicle-mediated transport to the plasma membrane. Each is linked with CCDC122 in more than 9 cancer types. Because this analysis shows association rather than direction, both CCDC122-to-partner and partner-to-CCDC122 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of protein localization to plasma membrane grouped by CCDC122-low versus CCDC122-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC122→partner) and Y-score (partner→CCDC122) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Establishment of protein localization to plasma membrane →	+0.106	+1.310	<.001	.001	3	9
BONE	Integrin-mediated signaling pathway →	+0.204	+1.398	.004	<.001	3	9
BONE	Vesicle-mediated transport to the plasma membrane →	+0.068	+1.143	.001	.003	2	10
LUNG_NSCLC_LUAD	Negative regulation of protein modification process →	+0.053	+0.878	<.001	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Negative regulation of hematopoietic stem cell differentiation →	+0.145	+0.745	<.001	.002	3	9
URINARY_TRACT	Response to acid chemical →	+0.083	+1.349	.001	.002	2	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,526 associations by consensus.

Establishment of protein localization to plasma membrane by CCDC122 expression — BONE

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