CCDC122

Across TCGA cell cohorts, CCDC122 mutation is significantly associated with the mutation status of many other genes, with 1,437 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC122-associated genes across cancer lineages are CCNK, NEFH, and DUOX1. Each is linked with CCDC122 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC122-to-partner and partner-to-CCDC122 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CCNK grouped by CCDC122-low versus CCDC122-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC122→partner) and Y-score (partner→CCDC122) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	CCNK →	+5.014	+5.584	.003	.003	1	3
BLOOD_Lymphoma	NEFH →	+4.429	+5.247	.005	.005	1	2
BLOOD_Lymphoma	DUOX1 →	+4.014	+4.969	.008	.008	1	2
BLOOD_Lymphoma	UHRF2 →	+4.429	+5.247	.005	.005	1	2
BLOOD_Lymphoma	CRIM1 →	+4.014	+4.969	.008	.008	1	2
BLOOD_Lymphoma	GPR137B →	+4.429	+5.247	.005	.005	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,437 associations by consensus.

CCNK by CCDC122 expression — BLOOD_Lymphoma

Explore this box plot interactively →