CCDC120

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CCDC120 mutation is significantly associated with the RNA expression of many other genes, with 2,031 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC120-associated genes across cancer lineages are TRAJ12, RNA5SP327, and RNU5E-9P. Each is linked with CCDC120 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC120-to-partner and partner-to-CCDC120 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TRAJ12 grouped by CCDC120-low versus CCDC120-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC120→partner) and Y-score (partner→CCDC120) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECTRAJ12 →+0.452+1.871<.001.00133
BRCARNA5SP327 →+0.251+4.639<.001.00533
COADRNU5E-9P →+0.166+4.409<.001.00433
BRCALINC01859 →+0.121+3.740<.001.00332
UCECCENPU →+0.641+3.628<.001.00132
UCECPTTG1 →+0.705+2.818<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,031 associations by consensus.

TRAJ12 by CCDC120 expression — UCEC

Box plot of TRAJ12 in CCDC120-low vs CCDC120-high samples in UCEC.

Explore this box plot interactively →

Exploration