CCDC120

Across TCGA pan-cancer cohorts, CCDC120 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of CCDC120’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where CCDC120 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CCDC120 is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

COAD, KIRC, and KICH are the cancer types where CCDC120 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CCDC120 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	IV	+1.061	<.001	12	view →
KIRC	Male	II,III,IV	−0.455	<.001	10	view →
KICH	Male	II,III,IV	−1.337	<.001	9	view →
LIHC	All	II,III,IV	+0.889	<.001	9	view →
LUSC	All	III,IV	+1.446	<.001	8	view →
LUAD	All	II,III,IV	+0.674	<.001	8	view →
BLCA	All	All	+0.922	.006	6	view →
BRCA	All	All	+0.488	<.001	6	view →
CHOL	Male	All	+2.233	<.001	4	view →
THCA	All	All	+0.291	.003	4	view →
HNSC	All	II,III,IV	−0.403	.020	3	view →
READ	Female	All	+1.316	.003	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

CCDC120–COAD

Open the COAD breakdown →