CCDC120

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, CCDC120 mutation is significantly associated with the RNA expression of many other genes, with 1,069 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CCDC120-associated genes across cancer lineages are TARM1, ASB17, and DCAF4L2. Each is linked with CCDC120 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC120-to-partner and partner-to-CCDC120 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TARM1 grouped by CCDC120-low versus CCDC120-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC120→partner) and Y-score (partner→CCDC120) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
URINARY_TRACTTARM1 →+0.026+5.087<.001.00431
OVARYASB17 →+0.014+4.222<.001.00631
OVARYDCAF4L2 →+0.485+4.321<.001.00431
OVARYOR2H1 →+0.023+4.444<.001.00131
OVARYOR12D2 →+0.037+3.700<.001.00531
BLOOD_LymphomaBMX →+1.082+4.350<.001.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,069 associations by consensus.

TARM1 by CCDC120 expression — URINARY_TRACT

Box plot of TARM1 in CCDC120-low vs CCDC120-high samples in URINARY_TRACT.

Explore this box plot interactively →

Exploration