CCDC117

Across TCGA patient cohorts, CCDC117 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,081 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CCDC117-associated proteins across cancer lineages are TRMT2A, XRCC1, and ZNF326. Each is linked with CCDC117 in more than 6 cancer types. Because this analysis shows association rather than direction, both CCDC117-to-partner and partner-to-CCDC117 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC117 versus TRMT2A in LSCC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC117→partner) and Y-score (partner→CCDC117) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TRMT2A →	+0.293	+0.507	<.001	<.001	3	7
BRCA	XRCC1 →	+0.440	+0.984	<.001	<.001	3	5
HNSC	ZNF326 →	+0.546	+0.801	<.001	<.001	3	5
LSCC	RFC4 →	+0.492	+0.495	<.001	<.001	3	5
LSCC	RFC5 →	+0.384	+0.537	<.001	<.001	3	5
GBM	SF3A1 →	+0.180	+0.261	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,081 associations by consensus.

CCDC117 vs TRMT2A — LSCC

Explore this scatter interactively →