CCDC116

Across TCGA patient cohorts, CCDC116 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,128 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible CCDC116-associated GO terms across cancer lineages are Positive regulation of double-strand break repair, RNA export from nucleus, and Protein methylation. Each is linked with CCDC116 in more than 26 cancer types. Because this analysis shows association rather than direction, both CCDC116-to-partner and partner-to-CCDC116 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of double-strand break repair grouped by CCDC116-low versus CCDC116-high in SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC116→partner) and Y-score (partner→CCDC116) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SCLC	Positive regulation of double-strand break repair →	+0.109	+0.396	<.001	<.001	3	27
SCLC	RNA export from nucleus →	+0.090	+0.268	.001	<.001	3	27
SCLC	Protein methylation →	+0.073	+0.338	<.001	<.001	3	27
SCLC	Obsolete histone modification →	+0.068	+0.305	<.001	<.001	3	27
SCLC	Obsolete histone methylation →	+0.110	+0.258	<.001	<.001	3	27
STAD	Obsolete positive regulation of histone methylation →	+0.069	+0.217	<.001	<.001	3	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,128 associations by consensus.

Positive regulation of double-strand break repair by CCDC116 expression — SCLC

Explore this box plot interactively →