CCDC116

Across TCGA cell cohorts, CCDC116 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,880 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CCDC116-associated GO terms across cancer lineages are Symbiont-mediated disruption of host cellular anatomical structure, Symbiont-mediated disruption of host anatomical structure, and Microtubule cytoskeleton organization involved in mitosis. Each is linked with CCDC116 in more than 13 cancer types. Because this analysis shows association rather than direction, both CCDC116-to-partner and partner-to-CCDC116 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Symbiont-mediated disruption of host cellular anatomical structure grouped by CCDC116-low versus CCDC116-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC116→partner) and Y-score (partner→CCDC116) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Symbiont-mediated disruption of host cellular anatomical structure →	+0.141	+0.218	.006	.003	3	14
OESOPHAGUS	Symbiont-mediated disruption of host anatomical structure →	+0.141	+0.218	.006	.003	3	14
CNS	Microtubule cytoskeleton organization involved in mitosis →	+0.053	+0.259	<.001	<.001	3	12
LUNG_SCLC	Protein localization to chromosome →	+0.095	+0.276	<.001	<.001	3	11
UPPER_AERODIGESTIVE_TRACT	Spindle localization →	+0.063	+0.258	.003	.005	3	11
OESOPHAGUS	Microtubule polymerization →	+0.121	+0.227	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,880 associations by consensus.

Symbiont-mediated disruption of host cellular anatomical structure by CCDC116 expression — OESOPHAGUS

Explore this box plot interactively →