CCDC115

Across TCGA cell cohorts, CCDC115 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,939 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CCDC115-associated GO terms across cancer lineages are Membrane fusion, Organelle membrane fusion, and Cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Each is linked with CCDC115 in more than 9 cancer types. Because this analysis shows association rather than direction, both CCDC115-to-partner and partner-to-CCDC115 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Membrane fusion grouped by CCDC115-low versus CCDC115-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC115→partner) and Y-score (partner→CCDC115) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Membrane fusion →	+0.049	+0.700	.002	<.001	3	10
SOFT_TISSUE	Organelle membrane fusion →	+0.051	+0.469	.001	.001	3	9
PANCREAS	Cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	-0.102	-0.439	<.001	<.001	3	8
SOFT_TISSUE	Endosome organization →	+0.056	+0.583	.003	<.001	3	8
OVARY	Vacuolar transport →	+0.053	+0.631	.001	.001	2	9
SOFT_TISSUE	Golgi vesicle transport →	+0.049	+0.505	.002	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,939 associations by consensus.

Membrane fusion by CCDC115 expression — BONE

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