CCDC114

Across TCGA patient cohorts, CCDC114 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,157 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CCDC114-associated GO terms across cancer lineages are Motile cilium assembly, Regulation of protein folding, and Cytoskeleton-dependent intracellular transport. Each is linked with CCDC114 in more than 24 cancer types. Because this analysis shows association rather than direction, both CCDC114-to-partner and partner-to-CCDC114 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Motile cilium assembly grouped by CCDC114-low versus CCDC114-high in UCEC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC114→partner) and Y-score (partner→CCDC114) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Motile cilium assembly →	+0.076	+2.375	<.001	<.001	3	25
STAD	Regulation of protein folding →	+0.084	+0.394	<.001	<.001	3	24
ESCA	Cytoskeleton-dependent intracellular transport →	+0.053	+0.397	<.001	<.001	3	24
STAD	Positive regulation of amide metabolic process →	+0.070	+0.205	<.001	<.001	2	25
STAD	Positive regulation of DNA repair →	+0.072	+0.275	<.001	<.001	3	24
ESCA	Morphogenesis of embryonic epithelium →	+0.041	+0.365	<.001	<.001	3	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,157 associations by consensus.

Motile cilium assembly by CCDC114 expression — UCEC

Explore this box plot interactively →