CCDC114

Across TCGA cell cohorts, CCDC114 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,664 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CCDC114-associated GO terms across cancer lineages are Sperm motility, Flagellated sperm motility, and Cilium or flagellum-dependent cell motility. Each is linked with CCDC114 in more than 11 cancer types. Because this analysis shows association rather than direction, both CCDC114-to-partner and partner-to-CCDC114 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Sperm motility grouped by CCDC114-low versus CCDC114-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC114→partner) and Y-score (partner→CCDC114) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Sperm motility →	-0.103	-0.845	.004	.005	3	12
LUNG_SCLC	Flagellated sperm motility →	-0.103	-0.845	.004	.005	3	12
UPPER_AERODIGESTIVE_TRACT	Cilium or flagellum-dependent cell motility →	-0.084	-0.291	<.001	.008	3	11
UPPER_AERODIGESTIVE_TRACT	Cilium-dependent cell motility →	-0.084	-0.291	<.001	.008	3	11
UPPER_AERODIGESTIVE_TRACT	Regulation of syncytium formation by plasma membrane fusion →	+0.092	+0.310	<.001	.004	3	11
BONE	Positive regulation of intracellular steroid hormone receptor signaling pathway →	+0.168	+0.653	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,664 associations by consensus.

Sperm motility by CCDC114 expression — LUNG_SCLC

Explore this box plot interactively →