CCDC113

Across TCGA pan-cancer cohorts, CCDC113 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated CCDC113 data layer compared with 8 for mutation status.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher CCDC113 RNA is associated with better overall survival. In most high-consensus cancer types, elevated CCDC113 expression acts as an unfavorable survival marker, although some lineages such as READ and ACC show a favorable association.

READ, HNSC, and MESO are the cancer types where CCDC113 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	OS	Tertile	All	0.986	0.859	.002	87	view →
HNSC	OS	Quartile	All	0.679	0.824	<.001	52	view →
MESO	OS	Quartile	All	0.298	0.558	.002	47	view →
THCA	DFS	Tertile	IV	0.395	0.847	.002	44	view →
ACC	DFS	Median	III,IV	0.590	0.103	.002	36	view →
BLCA	DFS	Median	All	0.169	0.499	.001	35	view →
UCEC	OS	Quartile	III,IV	0.925	0.756	.004	26	view →
KIRC	OS	Tertile	All	0.582	0.708	.010	22	view →
LUSC	OS	Median	IV	0.255	0.851	.021	18	view →
SKCM	DFS	Tertile	II,III,IV	0.330	0.184	.002	17	view →
CESC	DFS	Median	All	0.765	0.875	.004	16	view →
LUAD	OS	Quartile	II,III,IV	0.509	0.100	.009	14	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

CCDC113–READ (OS)

Open the READ breakdown →