CCDC113

Across TCGA pan-cancer cohorts, CCDC113 RNA differs between tumor and matched normal tissue in 11 of 18 cancer types tested, making tumor–normal expression one of CCDC113’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where CCDC113 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CCDC113 is over-expressed in tumor, although a few such as KIRC and KICH show the opposite, repressed pattern.

COAD, KIRP, and KIRC are the cancer types where CCDC113 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CCDC113 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	III,IV	+1.483	<.001	11	view →
KIRP	All	II,III,IV	+1.380	<.001	11	view →
KIRC	Male	II,III,IV	−0.875	<.001	11	view →
KICH	All	All	−0.778	<.001	7	view →
BRCA	All	All	+0.249	.009	6	view →
STAD	All	All	+0.425	.026	5	view →
CHOL	Male	All	+1.973	<.001	4	view →
LIHC	All	All	+0.434	<.001	4	view →
THCA	Male	All	−0.401	<.001	3	view →
READ	All	All	+1.063	.018	2	view →
LUSC	All	II,III,IV	−0.687	.042	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 11 strongest of 11 lineages.

CCDC113–COAD

Open the COAD breakdown →