CCDC112

Across TCGA patient cohorts, CCDC112 mutation is significantly associated with the RNA expression of many other genes, with 2,555 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC112-associated genes across cancer lineages are RN7SL248P, GAGE13, and RNA5SP147. Each is linked with CCDC112 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC112-to-partner and partner-to-CCDC112 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by CCDC112-low versus CCDC112-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC112→partner) and Y-score (partner→CCDC112) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL248P →	+0.046	+2.783	<.001	.009	3	2
BRCA	GAGE13 →	+0.064	+6.049	<.001	<.001	3	1
BRCA	RNA5SP147 →	+0.207	+4.324	<.001	.008	3	1
BRCA	RNU6-909P →	+0.713	+4.473	<.001	.001	3	1
BRCA	RNU6-844P →	+0.747	+3.796	.001	.005	3	1
BRCA	LINC02282 →	+0.209	+3.646	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,555 associations by consensus.

RN7SL248P by CCDC112 expression — UCEC

Explore this box plot interactively →