CCDC110

Across TCGA patient cohorts, CCDC110 mutation is significantly associated with the RNA expression of many other genes, with 3,721 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC110-associated genes across cancer lineages are TIMM22, CALHM6, and RNU6-740P. Each is linked with CCDC110 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC110-to-partner and partner-to-CCDC110 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TIMM22 grouped by CCDC110-low versus CCDC110-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC110→partner) and Y-score (partner→CCDC110) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TIMM22 →	+0.427	+3.007	<.001	<.001	3	3
UCEC	CALHM6 →	+0.907	+2.513	<.001	<.001	3	3
SKCM	RNU6-740P →	+0.128	+4.640	<.001	.003	3	3
UCEC	BAG1 →	+0.414	+2.010	<.001	.005	3	3
UCEC	CAMTA2 →	+0.391	+2.111	<.001	<.001	3	3
UCEC	CD86 →	+0.514	+2.098	.002	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,721 associations by consensus.

TIMM22 by CCDC110 expression — UCEC

Explore this box plot interactively →