CCDC110

Across TCGA cell cohorts, CCDC110 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,392 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible CCDC110-associated GO terms across cancer lineages are Establishment of vesicle localization, Positive regulation of interleukin-8 production, and Vesicle targeting, to, from or within Golgi. Each is linked with CCDC110 in more than 10 cancer types. Because this analysis shows association rather than direction, both CCDC110-to-partner and partner-to-CCDC110 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of vesicle localization grouped by CCDC110-low versus CCDC110-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC110→partner) and Y-score (partner→CCDC110) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Establishment of vesicle localization →	+0.066	+1.499	<.001	<.001	3	11
LUNG_NSCLC_LUSC	Positive regulation of interleukin-8 production →	-0.101	-0.754	<.001	.005	3	10
OESOPHAGUS	Vesicle targeting, to, from or within Golgi →	+0.089	+0.815	<.001	.001	3	9
OVARY	Respiratory electron transport chain →	+0.080	+0.592	<.001	<.001	3	9
KIDNEY	Phospholipase C-activating G protein-coupled receptor signaling pathway →	-0.060	-0.570	.001	.009	3	8
LUNG_SCLC	Aerobic electron transport chain →	+0.094	+1.261	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,392 associations by consensus.

Establishment of vesicle localization by CCDC110 expression — LUNG_SCLC

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