CCDC106

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, CCDC106 protein abundance is significantly associated with the RNA expression of many other genes, with 2,276 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible CCDC106-associated genes across cancer lineages are ABCD3, TTBK2, and CEP20. Each is linked with CCDC106 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC106-to-partner and partner-to-CCDC106 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CCDC106 versus ABCD3 in BRCA, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC106→partner) and Y-score (partner→CCDC106) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BRCAABCD3 →+0.986+0.394<.001.00132
LSCCTTBK2 →+0.608+0.479<.001.00132
HNSCCEP20 →+0.586+0.439.005.00532
LSCCLONRF2 →+1.474+0.557<.001<.00132
HNSCCNTD1 →+0.783+0.463.002.00132
BRCATALDO1 →-0.588-0.481<.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,276 associations by consensus.

CCDC106 vs ABCD3 — BRCA

Per-sample scatter of CCDC106 vs ABCD3 in BRCA (Pearson r = 0.32).

Explore this scatter interactively →

Exploration