CCDC106

Across TCGA patient cohorts, CCDC106 mutation is significantly associated with the RNA expression of many other genes, with 1,141 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC106-associated genes across cancer lineages are SNORD113-2, RNU6-1093P, and MIR1193. Each is linked with CCDC106 in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC106-to-partner and partner-to-CCDC106 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD113-2 grouped by CCDC106-low versus CCDC106-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC106→partner) and Y-score (partner→CCDC106) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	SNORD113-2 →	+0.760	+4.807	<.001	.004	3	2
COAD	RNU6-1093P →	+0.658	+4.542	<.001	.001	3	2
COAD	MIR1193 →	+0.616	+5.824	<.001	.001	3	2
LUSC	MTND4LP17 →	+0.236	+6.102	<.001	.001	3	2
LUAD	RAB42P1 →	+0.233	+4.273	.006	.003	3	2
LUAD	RNU6-659P →	+0.312	+4.502	.006	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,141 associations by consensus.

SNORD113-2 by CCDC106 expression — COAD

Explore this box plot interactively →