CCDC106

Across TCGA cell cohorts, CCDC106 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,871 significant associations in total. BONE shows the largest number of these associations.

The most reproducible CCDC106-associated GO terms across cancer lineages are tRNA transcription, G1 to G0 transition, and Regulation of blood-brain barrier permeability. Each is linked with CCDC106 in more than 8 cancer types. Because this analysis shows association rather than direction, both CCDC106-to-partner and partner-to-CCDC106 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, tRNA transcription grouped by CCDC106-low versus CCDC106-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC106→partner) and Y-score (partner→CCDC106) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	tRNA transcription →	+0.118	+1.792	<.001	.008	3	9
BONE	G1 to G0 transition →	+0.217	+1.487	<.001	<.001	3	8
LUNG_NSCLC_LUSC	Regulation of blood-brain barrier permeability →	-0.303	-1.517	.003	.003	3	8
OESOPHAGUS	Positive regulation of termination of RNA polymerase II transcription, poly(A)-coupled →	+0.160	+1.568	<.001	.001	3	8
LUNG_SCLC	Positive regulation of interleukin-18-mediated signaling pathway →	-0.974	-0.958	.004	.005	3	8
URINARY_TRACT	Locomotory exploration behavior →	+0.227	+1.888	<.001	.003	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,871 associations by consensus.

tRNA transcription by CCDC106 expression — STOMACH

Explore this box plot interactively →