CCDC105

Across TCGA patient cohorts, CCDC105 mutation is significantly associated with the RNA expression of many other genes, with 2,617 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC105-associated genes across cancer lineages are CAMTA2, MIR548T, and IL17RA. Each is linked with CCDC105 in more than 2 cancer types. Because this analysis shows association rather than direction, both CCDC105-to-partner and partner-to-CCDC105 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CAMTA2 grouped by CCDC105-low versus CCDC105-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC105→partner) and Y-score (partner→CCDC105) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CAMTA2 →	+0.466	+2.741	<.001	.003	3	3
CESC	MIR548T →	+0.265	+3.475	.009	.008	3	3
UCEC	IL17RA →	+0.412	+2.439	.001	.001	3	3
SKCM	GMEB1 →	+0.379	+2.019	.001	.005	3	3
UCEC	UTP15 →	+0.494	+2.660	<.001	<.001	3	2
UCEC	ZNF367 →	+0.876	+2.584	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,617 associations by consensus.

CAMTA2 by CCDC105 expression — UCEC

Explore this box plot interactively →