CCDC102B

Across TCGA patient cohorts, CCDC102B mutation is significantly associated with the total protein of many other genes, with 39 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CCDC102B-associated genes across cancer lineages are beta-Catenin, Ku80, and Annexin_VII. Each is linked with CCDC102B in more than 1 cancer types. Because this analysis shows association rather than direction, both CCDC102B-to-partner and partner-to-CCDC102B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, beta-Catenin grouped by CCDC102B-low versus CCDC102B-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CCDC102B→partner) and Y-score (partner→CCDC102B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	beta-Catenin →	+0.656	+2.821	.009	.035	3	2
UCEC	Ku80 →	+0.171	+1.598	.031	.006	3	2
UCEC	Annexin_VII →	-0.129	-2.584	.005	.010	3	2
UCEC	Shc_pY317 →	-0.192	-3.000	<.001	<.001	3	2
UCEC	Tuberin →	+0.279	+2.700	.001	.005	3	2
UCEC	C-Raf →	+0.138	+2.321	.004	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 39 associations by consensus.

beta-Catenin by CCDC102B expression — LUSC

Explore this box plot interactively →