CCAR1

Across TCGA pan-cancer cohorts, CCAR1 mass-spec protein is linked to patient survival in 7 of 34 cancer types, making it a survival-associated CCAR1 data layer compared with 26 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in colon adenocarcinoma (COAD), where higher CCAR1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated CCAR1 expression acts as an unfavorable survival marker, although some lineages such as COAD and LUAD show a favorable association.

COAD, HNSC, and LUAD are the cancer types where CCAR1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
COAD	DFS	Median	II,III,IV	1.000	0.911	.012	90	view →
HNSC	DFS	Quartile	III,IV	0.703	0.969	.004	61	view →
LUAD	OS	Median	III,IV	0.848	0.425	.008	17	view →
LSCC	OS	Quartile	All	0.915	0.668	.024	16	view →
GBM	DFS	Median	All	0.432	0.219	.014	10	view →
PDAC	DFS	Median	All	0.816	0.709	.012	8	view →
UCEC	OS	Median	All	0.981	0.867	.034	2	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

CCAR1–COAD (DFS)

Open the COAD breakdown →