CC2D2A

Across TCGA cell cohorts, CC2D2A mutation is significantly associated with the RNA expression of many other genes, with 628 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible CC2D2A-associated genes across cancer lineages are DPRX, CCER1, and MRGPRE. Each is linked with CC2D2A in more than 1 cancer types. Because this analysis shows association rather than direction, both CC2D2A-to-partner and partner-to-CC2D2A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DPRX grouped by CC2D2A-low versus CC2D2A-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CC2D2A→partner) and Y-score (partner→CC2D2A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	DPRX →	+0.038	+4.369	<.001	.008	3	2
CNS	CCER1 →	+0.012	+4.754	<.001	.005	3	2
SOFT_TISSUE	MRGPRE →	+0.039	+4.417	<.001	.004	3	1
SOFT_TISSUE	GPX6 →	+0.017	+4.369	<.001	.008	3	1
URINARY_TRACT	OR4F15 →	+0.138	+4.217	<.001	.005	3	1
URINARY_TRACT	DCDC2C →	+0.126	+4.217	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 628 associations by consensus.

DPRX by CC2D2A expression — SOFT_TISSUE

Explore this box plot interactively →