CC2D2A

Across TCGA pan-cancer cohorts, CC2D2A RNA differs between tumor and matched normal tissue in 14 of 18 cancer types tested, making tumor–normal expression one of CC2D2A’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where CC2D2A RNA is repressed in tumor relative to normal tissue. In most cancer types CC2D2A is over-expressed in tumor, although a few such as KICH and LUAD show the opposite, repressed pattern.

KICH, LUAD, and THCA are the cancer types where CC2D2A tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CC2D2A RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Female	II,III,IV	−2.542	<.001	11	view →
LUAD	Female	III,IV	−0.964	<.001	10	view →
THCA	Male	II,III,IV	−0.965	<.001	9	view →
BLCA	Male	All	−1.714	<.001	8	view →
UCEC	All	All	−1.690	<.001	8	view →
LUSC	Male	II,III,IV	−1.003	<.001	8	view →
BRCA	Female	II,III,IV	−0.732	<.001	6	view →
COAD	All	All	−0.547	.001	6	view →
KIRC	Male	II,III,IV	−0.500	<.001	6	view →
LIHC	All	All	+0.423	<.001	5	view →
STAD	All	All	−0.765	.009	4	view →
KIRP	Male	All	−0.524	.005	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 14 lineages.

CC2D2A–KICH

Open the KICH breakdown →