CC2D1B

Across TCGA patient cohorts, CC2D1B mutation is significantly associated with the RNA expression of many other genes, with 4,274 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CC2D1B-associated genes across cancer lineages are CSTF2, HDAC1, and KLRD1. Each is linked with CC2D1B in more than 2 cancer types. Because this analysis shows association rather than direction, both CC2D1B-to-partner and partner-to-CC2D1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CSTF2 grouped by CC2D1B-low versus CC2D1B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CC2D1B→partner) and Y-score (partner→CC2D1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CSTF2 →	+0.490	+2.332	<.001	<.001	3	3
UCEC	HDAC1 →	+0.302	+2.141	.004	.002	3	3
UCEC	KLRD1 →	+0.250	+1.887	.002	.002	3	3
UCEC	HAUS2 →	+0.709	+2.700	<.001	<.001	3	3
UCEC	TAF5 →	+0.476	+3.752	<.001	<.001	3	3
UCEC	ASAH2B →	+0.270	+1.523	.006	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,274 associations by consensus.

CSTF2 by CC2D1B expression — UCEC

Explore this box plot interactively →