CC2D1A

Across TCGA patient cohorts, CC2D1A mutation is significantly associated with the RNA expression of many other genes, with 3,687 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CC2D1A-associated genes across cancer lineages are IMP3, ZMYND19, and TMEM126A. Each is linked with CC2D1A in more than 3 cancer types. Because this analysis shows association rather than direction, both CC2D1A-to-partner and partner-to-CC2D1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IMP3 grouped by CC2D1A-low versus CC2D1A-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CC2D1A→partner) and Y-score (partner→CC2D1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IMP3 →	+0.246	+1.584	.007	.002	3	4
SKCM	ZMYND19 →	+0.413	+2.434	.003	.001	3	3
SKCM	TMEM126A →	+0.438	+3.195	.005	.009	3	3
UCEC	LPL →	-0.520	-1.584	.001	.002	3	3
COAD	CHAC2 →	+0.781	+3.321	<.001	.009	3	3
READ	UPP2-IT1 →	+0.126	+5.039	.002	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,687 associations by consensus.

IMP3 by CC2D1A expression — UCEC

Explore this box plot interactively →