CC2D1A

Across TCGA pan-cancer cohorts, CC2D1A RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of CC2D1A’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where CC2D1A RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CC2D1A is over-expressed in tumor, although a few such as COAD show the opposite, repressed pattern.

KIRP, LIHC, and HNSC are the cancer types where CC2D1A tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CC2D1A RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	All	II,III,IV	+0.613	<.001	10	view →
LIHC	Female	II,III,IV	+1.051	<.001	9	view →
HNSC	All	All	+0.383	<.001	8	view →
STAD	All	II,III,IV	+0.650	.002	6	view →
LUSC	All	All	+0.419	<.001	5	view →
UCEC	All	All	+0.599	.003	4	view →
BLCA	All	All	+0.462	.010	4	view →
THCA	All	All	+0.219	<.001	4	view →
CHOL	Female	All	+2.120	<.001	3	view →
COAD	Female	II,III,IV	−0.324	.034	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 10 strongest of 10 lineages.

CC2D1A–KIRP

Open the KIRP breakdown →