CBX8

Across TCGA patient cohorts, CBX8 RNA expression is significantly associated with the protein abundance of many other proteins, with 17,462 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CBX8-associated proteins across cancer lineages are DCAF7, SUPT16H, and SMARCA4. Each is linked with CBX8 in more than 5 cancer types. Because this analysis shows association rather than direction, both CBX8-to-partner and partner-to-CBX8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CBX8 versus DCAF7 in GBM, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CBX8→partner) and Y-score (partner→CBX8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	DCAF7 →	+0.263	+0.620	<.001	<.001	3	6
GBM	SUPT16H →	+0.351	+0.382	<.001	<.001	3	5
GBM	SMARCA4 →	+0.384	+0.482	<.001	<.001	3	5
GBM	VEZF1 →	+0.404	+0.396	<.001	<.001	3	4
COAD	VGLL4 →	+0.364	+0.436	<.001	<.001	3	4
GBM	YTHDF2 →	+0.223	+0.337	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,462 associations by consensus.

CBX8 vs DCAF7 — GBM

Explore this scatter interactively →