CBX7

Across TCGA patient cohorts, CBX7 protein abundance is significantly associated with the RNA expression of many other genes, with 6,598 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible CBX7-associated genes across cancer lineages are ZNF540, TGFBR3, and CDCA5. Each is linked with CBX7 in more than 3 cancer types. Because this analysis shows association rather than direction, both CBX7-to-partner and partner-to-CBX7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CBX7 versus ZNF540 in BRCA, with a Pearson correlation of 0.48.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBX7→partner) and Y-score (partner→CBX7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ZNF540 →	+0.614	+0.420	<.001	<.001	3	4
BRCA	TGFBR3 →	+1.446	+0.596	<.001	<.001	3	4
OV	CDCA5 →	-1.511	-1.016	.004	<.001	3	4
OV	BUB1 →	-1.293	-0.671	.004	.002	3	4
UCEC	FOXM1 →	-1.005	-0.481	.001	<.001	3	3
BRCA	E2F3 →	-0.745	-0.590	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,598 associations by consensus.

CBX7 vs ZNF540 — BRCA

Explore this scatter interactively →