CBX7

Across TCGA patient cohorts, CBX7 mutation is significantly associated with the RNA expression of many other genes, with 3,532 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CBX7-associated genes across cancer lineages are LINC00701, HMGN2P22, and RNA5SP413. Each is linked with CBX7 in more than 1 cancer types. Because this analysis shows association rather than direction, both CBX7-to-partner and partner-to-CBX7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC00701 grouped by CBX7-low versus CBX7-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBX7→partner) and Y-score (partner→CBX7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	LINC00701 →	+0.273	+5.010	<.001	.009	3	2
COAD	HMGN2P22 →	+0.470	+4.181	<.001	.009	3	2
UCEC	RNA5SP413 →	+0.719	+1.746	.002	.006	3	2
UCEC	TRIM53CP →	+0.429	+1.635	<.001	.008	3	2
SKCM	RPL35AP →	+0.188	+4.823	<.001	<.001	3	2
SKCM	LINC02658 →	+0.057	+4.469	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,532 associations by consensus.

LINC00701 by CBX7 expression — CESC

Explore this box plot interactively →