Across TCGA pan-cancer cohorts, CBX5P1 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of CBX5P1’s most consistent transcriptional readouts.
The strongest signal is observed in breast invasive carcinoma (BRCA), where CBX5P1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CBX5P1 is over-expressed in tumor.
BRCA, LIHC, and HNSC are the cancer types where CBX5P1 tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CBX5P1 RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.