Q-omics provides the consensus-scored CBX5P1 profile across patient tissues and cancer cell-line models. CBX5P1 expression is associated with patient survival in 18 of 34 cancer types, with the highest sampling consensus in KIRC. Among the 18 cancer types available for tumor–normal comparison, CBX5P1 is differentially expressed in 4, with the highest sampling consensus in BRCA. Additionally, CBX5P1 RNA expression shows 13,817 significant gene co-expression associations, with the highest sampling consensus in DLBC. Together, these results highlight KIRC, BRCA, and DLBC as cancer lineages where CBX5P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for CBX5P1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes CBX5P1 survival associations across molecular data types. CBX5P1 RNA expression shows survival associations in the most cancer types (18). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible CBX5P1 RNA expression–survival associations across cancer types. High CBX5P1 expression shows unfavorable associations in KIRC, UCEC, UVM and ACC, but favorable associations in READ and HNSC. The KIRC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .001). Together, the overview and detailed table identify KIRC as the clearest survival context for CBX5P1 RNA expression.
This table summarizes CBX5P1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 4. The strongest signals are observed in BRCA for RNA.
This table ranks reproducible tumor–normal expression differences for CBX5P1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. CBX5P1 shows higher tumor expression in BRCA, LIHC, HNSC and LUSC. The BRCA box plot shows higher CBX5P1 RNA expression in tumor versus normal tissue (log2 FC = +0.207, t-test p = .012).
This table shows molecular features associated with CBX5P1 in patient tissues and cancer cell lines. In patient samples, CBX5P1 shows the broadest associations at the RNA and protein expression levels, with DLBC recurring as the lineage with the largest associated feature set.
