CBX4

Across TCGA patient cohorts, CBX4 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,161 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CBX4-associated proteins across cancer lineages are CBX4_S291, CBX4_S415, and ZNF219_S114. Each is linked with CBX4 in more than 5 cancer types. Because this analysis shows association rather than direction, both CBX4-to-partner and partner-to-CBX4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CBX4 versus CBX4_S291 in BRCA, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CBX4→partner) and Y-score (partner→CBX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CBX4_S291 →	+0.772	+1.025	.001	<.001	3	6
BRCA	CBX4_S415 →	+0.762	+0.878	<.001	.005	3	6
GBM	ZNF219_S114 →	+0.838	+0.363	<.001	<.001	3	4
BRCA	TXNDC5 →	-0.642	-0.968	<.001	<.001	3	4
COAD	MYG1 →	+0.271	+0.455	.001	.008	2	4
HNSC	ARHGAP18_S66 →	-1.020	-0.517	<.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,161 associations by consensus.

CBX4 vs CBX4_S291 — BRCA

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