CBX4

Across TCGA patient cohorts, CBX4 protein abundance is significantly associated with the RNA expression of many other genes, with 15,149 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CBX4-associated genes across cancer lineages are LINC01977, SLC2A9, and MFNG. Each is linked with CBX4 in more than 4 cancer types. Because this analysis shows association rather than direction, both CBX4-to-partner and partner-to-CBX4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CBX4 versus LINC01977 in BRCA, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBX4→partner) and Y-score (partner→CBX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	LINC01977 →	+0.750	+0.405	<.001	<.001	3	5
LSCC	SLC2A9 →	-0.824	-0.317	<.001	<.001	3	5
GBM	MFNG →	-0.613	-0.323	<.001	<.001	3	4
GBM	NCF2 →	-0.951	-0.408	<.001	<.001	3	4
GBM	RRAS →	-0.794	-0.392	<.001	<.001	3	4
GBM	RAC2 →	-0.896	-0.307	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,149 associations by consensus.

CBX4 vs LINC01977 — BRCA

Explore this scatter interactively →