CBX4

Across TCGA patient cohorts, CBX4 protein abundance is significantly associated with the protein abundance of many other proteins, with 24,435 significant associations in total. GBM shows the largest number of these associations.

The most reproducible CBX4-associated proteins across cancer lineages are THRAP3, CBX4_S291, and CBX4_S415. Each is linked with CBX4 in more than 6 cancer types. Because this analysis shows association rather than direction, both CBX4-to-partner and partner-to-CBX4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CBX4 versus THRAP3 in GBM, with a Pearson correlation of 0.61.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CBX4→partner) and Y-score (partner→CBX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	THRAP3 →	+0.259	+0.367	<.001	<.001	3	7
BRCA	CBX4_S291 →	+0.839	+0.431	<.001	<.001	3	7
BRCA	CBX4_S415 →	+0.705	+0.465	<.001	<.001	3	7
BRCA	ACTR2 →	-0.233	-0.315	<.001	<.001	3	6
CCRCC	API5_S464 →	+0.575	+0.265	<.001	<.001	3	6
GBM	SF3A2 →	+0.293	+0.358	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 24,435 associations by consensus.

CBX4 vs THRAP3 — GBM

Explore this scatter interactively →