CBX4

Across TCGA cell cohorts, CBX4 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,952 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible CBX4-associated GO terms across cancer lineages are Regulation of brown fat cell differentiation, Copper ion export, and Negative regulation of brown fat cell differentiation. Each is linked with CBX4 in more than 14 cancer types. Because this analysis shows association rather than direction, both CBX4-to-partner and partner-to-CBX4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of brown fat cell differentiation grouped by CBX4-low versus CBX4-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CBX4→partner) and Y-score (partner→CBX4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of brown fat cell differentiation →	+0.132	+1.420	.003	.002	3	15
BLOOD_Leukemia	Copper ion export →	-0.151	-1.040	<.001	<.001	3	14
SKIN	Negative regulation of brown fat cell differentiation →	+0.179	+1.310	<.001	<.001	3	14
BONE	Calcium-independent cell-matrix adhesion →	+0.247	+1.343	<.001	<.001	3	13
BONE	Pre-mRNA catabolic process →	+0.182	+0.948	<.001	<.001	3	13
URINARY_TRACT	Regulation of proteasomal protein catabolic process →	+0.059	+0.998	.003	.008	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,952 associations by consensus.

Regulation of brown fat cell differentiation by CBX4 expression — STOMACH

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