CBX1

Across TCGA patient cohorts, CBX1 RNA expression is significantly associated with the protein abundance of many other proteins, with 20,659 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible CBX1-associated proteins across cancer lineages are RFC1, HDAC2, and MDC1. Each is linked with CBX1 in more than 6 cancer types. Because this analysis shows association rather than direction, both CBX1-to-partner and partner-to-CBX1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, CBX1 versus RFC1 in GBM, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (CBX1→partner) and Y-score (partner→CBX1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	RFC1 →	+0.320	+0.436	.001	.002	3	7
LSCC	HDAC2 →	+0.258	+0.689	<.001	<.001	3	7
LUAD	MDC1 →	+0.351	+0.515	<.001	<.001	3	7
GBM	ZMYM3 →	+0.419	+0.575	<.001	.001	3	6
LSCC	TOP2A →	+0.951	+0.809	<.001	<.001	3	6
LSCC	RFC2 →	+0.500	+0.859	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,659 associations by consensus.

CBX1 vs RFC1 — GBM

Explore this scatter interactively →