Across TCGA patient cohorts, CBWD6 mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CBWD6-associated genes across cancer lineages are KLF17P2, MIR3621, and KRTAP21-1. Each is linked with CBWD6 in more than 1 cancer types. Because this analysis shows association rather than direction, both CBWD6-to-partner and partner-to-CBWD6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBWD6→partner) and Y-score (partner→CBWD6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	KLF17P2 →	+0.089	+7.954	<.001	.008	3	1
HNSC	MIR3621 →	+0.308	+7.954	<.001	.008	3	1
UCEC	KRTAP21-1 →	+0.161	+4.827	<.001	.001	3	1
UCEC	TRAJ57 →	+0.659	+3.903	.002	.006	3	1
UCEC	RPS3AP33 →	+0.118	+4.109	<.001	.004	3	1
UCEC	RNU4-65P →	+0.305	+4.868	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

Exploration

CBWD6 survival (RNA) · tumor vs normal (RNA) · all CBWD6 data types