Across TCGA pan-cancer cohorts, CBWD4P RNA differs between tumor and matched normal tissue in 10 of 18 cancer types tested, making tumor–normal expression one of CBWD4P’s most consistent transcriptional readouts.
The strongest signal is observed in colon adenocarcinoma (COAD), where CBWD4P RNA is more highly expressed in tumor relative to normal tissue. In most cancer types CBWD4P is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.
COAD, HNSC, and KIRC are the cancer types where CBWD4P tumor–normal differential expression is most reproducible.
RNA tumor vs normal associations by lineage
Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in CBWD4P RNA (log2); positive values indicate higher expression in tumor. p-values are from the differential-expression test.