Q-omics provides the consensus-scored CBWD4P profile across patient tissues and cancer cell-line models. CBWD4P expression is associated with patient survival in 16 of 34 cancer types, with the highest sampling consensus in ACC. Among the 18 cancer types available for tumor–normal comparison, CBWD4P is differentially expressed in 10, with the highest sampling consensus in COAD. Additionally, CBWD4P RNA expression shows 13,619 significant gene co-expression associations, with the highest sampling consensus in UVM. Together, these results highlight ACC, COAD, and UVM as cancer lineages where CBWD4P shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for CBWD4P — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes CBWD4P survival associations across molecular data types. CBWD4P RNA expression shows survival associations in the most cancer types (16). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible CBWD4P RNA expression–survival associations across cancer types. High CBWD4P expression shows unfavorable associations in ACC, KIRC and READ, but favorable associations in BLCA, BRCA and CESC. The ACC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify ACC as the clearest survival context for CBWD4P RNA expression.
This table summarizes CBWD4P tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 10. The strongest signals are observed in COAD for RNA.
This table ranks reproducible tumor–normal expression differences for CBWD4P. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. CBWD4P shows higher tumor expression in COAD, HNSC, KIRC, LUSC, STAD and READ. The COAD box plot shows higher CBWD4P RNA expression in tumor versus normal tissue (log2 FC = +0.579, t-test p < 0.001).
This table shows molecular features associated with CBWD4P in patient tissues and cancer cell lines. In patient samples, CBWD4P shows the broadest associations at the RNA and protein expression levels, with UVM recurring as the lineage with the largest associated feature set.
