Across TCGA patient cohorts, CBWD3 mutation is significantly associated with the RNA expression of many other genes, with 63 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CBWD3-associated genes across cancer lineages are CICP28, SPDYE20P, and MIR6894. Each is linked with CBWD3 in more than 1 cancer types. Because this analysis shows association rather than direction, both CBWD3-to-partner and partner-to-CBWD3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBWD3→partner) and Y-score (partner→CBWD3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CICP28 →	+0.035	+3.766	<.001	.001	3	1
UCEC	SPDYE20P →	+0.262	+3.521	.004	.007	3	1
UCEC	MIR6894 →	+1.044	+3.818	<.001	.001	3	1
UCEC	MIR4672 →	+0.586	+3.041	.001	.008	3	1
UCEC	RN7SL140P →	+0.142	+4.260	.004	.007	3	1
UCEC	SNORA59B →	+0.313	+3.818	.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 63 associations by consensus.

Exploration

CBWD3 survival (RNA) · tumor vs normal (RNA) · all CBWD3 data types