CBWD2

Across TCGA patient cohorts, CBWD2 mutation is significantly associated with the RNA expression of many other genes, with 983 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CBWD2-associated genes across cancer lineages are OR11H12, LINC00363, and GCATP1. Each is linked with CBWD2 in more than 1 cancer types. Because this analysis shows association rather than direction, both CBWD2-to-partner and partner-to-CBWD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR11H12 grouped by CBWD2-low versus CBWD2-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBWD2→partner) and Y-score (partner→CBWD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	OR11H12 →	+0.049	+7.741	<.001	.009	3	2
UCEC	LINC00363 →	+0.146	+3.153	<.001	.006	3	2
UCEC	GCATP1 →	+0.367	+2.627	.002	.006	3	1
UCEC	H2BC14 →	+0.672	+2.617	<.001	.005	3	1
UCEC	MIR6864 →	+0.828	+2.587	<.001	<.001	3	1
UCEC	PCCA-DT →	+0.694	+3.491	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 983 associations by consensus.

OR11H12 by CBWD2 expression — COAD

Explore this box plot interactively →