CBWD2

Across TCGA cell cohorts, CBWD2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,547 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible CBWD2-associated GO terms across cancer lineages are Replication fork processing, Recombinational repair, and Negative regulation of RNA splicing. Each is linked with CBWD2 in more than 12 cancer types. Because this analysis shows association rather than direction, both CBWD2-to-partner and partner-to-CBWD2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Replication fork processing grouped by CBWD2-low versus CBWD2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (CBWD2→partner) and Y-score (partner→CBWD2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Replication fork processing →	+0.095	+0.737	<.001	<.001	3	13
BLOOD_Myeloma	Recombinational repair →	+0.073	+0.898	.001	.001	3	12
BLOOD_Lymphoma	Negative regulation of RNA splicing →	+0.102	+0.806	<.001	<.001	3	12
LUNG_SCLC	Late viral transcription →	+0.153	+0.859	<.001	<.001	3	12
LUNG_SCLC	Spliceosomal complex assembly →	+0.104	+0.789	<.001	<.001	3	12
SOFT_TISSUE	DNA-templated DNA replication maintenance of fidelity →	+0.093	+0.744	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,547 associations by consensus.

Replication fork processing by CBWD2 expression — SOFT_TISSUE

Explore this box plot interactively →