CBLN4

Across TCGA patient cohorts, CBLN4 mutation is significantly associated with the RNA expression of many other genes, with 2,638 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible CBLN4-associated genes across cancer lineages are RNU1-35P, RNU6-1127P, and RPS27P20. Each is linked with CBLN4 in more than 1 cancer types. Because this analysis shows association rather than direction, both CBLN4-to-partner and partner-to-CBLN4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU1-35P grouped by CBLN4-low versus CBLN4-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (CBLN4→partner) and Y-score (partner→CBLN4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	RNU1-35P →	+0.235	+4.559	<.001	.006	3	2
COAD	RNU6-1127P →	+0.260	+4.399	.006	.006	3	2
LUSC	RPS27P20 →	+0.398	+4.105	<.001	.005	3	2
LUSC	MIR4799 →	+0.641	+5.485	<.001	<.001	3	2
UCEC	PPIL2 →	+0.345	+1.949	.001	.001	3	2
UCEC	TELO2 →	+0.354	+2.828	.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,638 associations by consensus.

RNU1-35P by CBLN4 expression — CESC

Explore this box plot interactively →